Notícias
Improving Compound Quality: Physical Chemistry and DMPK Properties in Drug
22/06/2012 12:29
The European Federation for Medicinal Chemistry (EFMC) is organising the 6th EFMC Short Course on Medicinal Chemistry
Improving Compound Quality: Physical Chemistry and DMPK Properties in Drug Discovery. Principles, Assays and Predictions
October 21-24, 2012
Castle "Oud Poelgeest", Oegstgeest, The Netherlands
This intensive course is intended for scientists working in the field, and the presentations will be given by senior scientists from industry. The number of participants will be limited to 35, to favour in depth discussion.
Course Outline
In modern drug discovery, it is important that the Medicinal Chemist understands how to balance potency and ADME properties in order to provide high quality compounds for progression to clinical studies. This short course will be a mixture of talks and worked exercises designed to further the understanding of DMPK.
The course will include:
- Outlines of the key DMPK in vitro assays: physicochemistry for ADME;
- Oral drug absorption;
- Fundamentals of drug distribution;
- drug metabolizing enzymes;
- drug transport proteins;
- basic PK principles and human PK prediction;
- PKPD relationships.
Course Organisers
Kevin Beaumont (Pfizer, US)
Henk Timmerman (VU University Amsterdam, The Netherlands)
Deadline for pre-registration: September 14, 2012
For more information and registration, please visit the website of the Course.
Symposium Secretariat
LD ORGANISATION
Tel : +32 10 45 47 77
Fax : +32 10 45 97 19
E-mail : secretariat@LDOrganisation.com
Url : http://www.LDOrganisation.com
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