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49th International Conference on Medicinal Chemistry

25/04/2013 09:11

Drug Discovery and Selection

When Chemical Biology meets Drug Design

RICT 2013 - 49th International Conference on Medicinal Chemistry

Nice (France) - July 3-5, 2013

Editorial: Striving for the High-hanging Fruits

Dr Joachim Mittendorf, Bayer HealthCare (Germany), has made us the pleasure to share his thoughts on the subject of the symposium.

For him, Drug discovery is operating in an environment that is becoming even more challenging. Apart from increasing regulatory hurdles, the reimbursement of a drug, which is crucial for success in the market, will depend on its breakthrough innovation potential, i.e. providing significant difference in the care for patients and convincing scientists, regulatory authorities, insurance companies, physicians and first and foremost the patients.

At the other end of the value chain, in the early stage of drug discovery the situation is changing towards a significantly increasing ratio of targets associated with an inherently poor chemical tractability. This does not only include targets with a low probability to bind small molecules such as those involving protein-protein interactions but also targets associated with highly demanding selectivity issues, challenging assay designs and incomplete or invalid secondary test cascades. Many of these targets can be modulated by antibodies or other macromolecules. However, this comes at the expense of parenteral application, which is considered less attractive for many therapeutic areas, not to mention the limitation to extracellular targets.

Read more..

Registration and Accommodation Booking

Register before May 15 to benefit from the early bird price.

All participants are invited to submit abstracts of scientific communications for poster presentations. Submitted abstracts will be peer-reviewed for their acceptance by the Organising Committee. Please note that your registration is required to access abstract submission, but payment is not mandatory at this stage. Accepted summaries will however only be published in the book of abstracts of the symposium, after full payment of the registration fee. Deadline for early registration and abstract submission: May 15, 2013

Find out more about Accommodation possibilities in Nice on the accommodation page. Low budget rooms at the University Campus are now also available!

RICT 2013 Symposium Secretariat
LD Organisation - Scientific Conference Producers
Tel : +32 10 45 47 77 
Fax : +32 10 45 97 19

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